Something that also seems to be an issue with build 7000 is threads that cannot be killed. Right now I’m stuck in a situation where I cannot open more (file) Explorer windows and I cannot close Internet Explorer. Even though I’m trying to end threads from Task Manager. Looks like this in Task Manager right now:

I’ve had the same problems with the Messenger process that couldn’t be killed. Could be because I’m not running as Admin? Time for a reboot.

Edit: I have just uninstalled Virtual CloneDrive (5.4.1.1) to see of it was causing problems related to restart and file handling, which some reports indicate. I’ve also downloaded a newer beta version of CloneDrive (5.4.2.3) which should support 64-bit Windows 7 better I’ve heard. Follow the discussion on TechNet.